Basis of antifungal resistance and it’s mitigation strategies

Fungal infections are emerging now a days causing wide spectrum of diseases in humans and animals mostly affecting patients with immunodeficiencies or chronic illness. As such we can see that rise fungal infection suffering from Covid-19. It has become measure challenge for clinicians to treat invasive as there is only limited classes antifungal agents available. So this causes the over use which gives opportunity pathogens develop resistance. The main five types nowadays mainly azoles, echinocandin, polyenes, alamines pyrimidine analogues. These compounds act through different mechanisms show fungicidal fungistatic effect. In response this, have developedcertain enable them escape overcome effects antifungals. Due these resistance against emerged worldwide.